Nexium is the trade name of the drug Esomeprazole used primarily to prevent the formation of stomach acid. Nexium comes under the class of drugs called PPIs or Proton Pump Inhibitors. PPIs are very effective in the inhibition of acid secretion. Doctors prescribe people to buy Nexium Generic, as it is used in the treatment of gastroesophageal reflux disease, dyspepsia, Zollinger-Ellison Syndrome and peptic ulcer disease.
How Nexium Treats Acidity?
The stomach is acidified by an enzyme called hydrogen potassium ATPase or H+/K+-ATPase. By inhibiting H+/K+-ATPase in the parietal cells of the stomach, acidity is significantly reduced. The (S)-(-)-enantiomer of omeprazole is Esomeprazole.
Other medical Uses of Nexium
In addition to treating Gastroesophageal Reflux disease and peptic ulcers, Nexium might also be used to prevent gastric ulcer. Infection caused by helicobacter pylori cause gastric ulcers or they can form as a result of using nonsteroidal anti-inflammatory drugs or (NSAIDs). Nexium is the perfect medication to deal with this type of ulcer. Heartburn symptoms, however, are not treated using this medication. Esomeprazole is also used in the maintenance of erosive esophagitis and gastrointestinal ulcers developed as a result of Crohn’s disease.
Nexium Drug interactions
Atazanavir, nelfinavir, and saquinavir are some antiretroviral drugs that should be avoided, because, Nexium may have an impact on the way these antiviral drugs are absorbed. Clopidogrel must also not be taken concurrently with Nexium. Any drug for whose absorption, pH is essential, must be avoided, as Nexium will impact their absorption. Methotrexate toxicity might occur if esomeprazole is used alongside methotrexate. Esomeprazole serum level may decrease when drugs such as rifampin are used concurrently with Nexium. Diazepam should also be avoided. St. John’s wort, erlotinib, iron supplements, and tacrolimus can all have interactions with this medication.
Guidelines to follow while taking Nexium
- Excessive intake of Nexium should be avoided and the sudden stoppage of the medicine can also have adverse effects. The doctor’s dosage recommendation must be strictly followed.
- Nexium is given normally for a four to eight-week course and some patients, who need more time to heal, might be suggested the second spell of administration.
- At least eight ounces of water must be taken along with Nexium.
- Crushing or chewing of Nexium is not advised as the effectiveness of the medication would go down.
- Nexium might be opened, the substance within, sprinkled over in apple sauce and consumed, but the powder mustn’t be stored for later use.
- Nexium is usually taken at least one hour before a meal. Vitamin B-12 deficiency can develop if the pill is taken for more than 3 years and the doctor would know when to stop the course.
Precautions to take before using Nexium Generic
- Children less than one month mustn’t be given this medication. Breastfeeding women must consult with a doctor before taking Nexium as it can get transferred to the baby through the breast milk. People can purchase Nexium and can use it as a short-term drug for children from age one to age seventeen.
- People who are allergic to drugs similar to esomeprazole will most likely be allergic to Nexium as well. People with liver disease, low magnesium levels in the blood, osteoporosis and osteopenia must inform the doctor about their problems before taking in the medication.
- People above the age of fifty who take the medicine for a prolonged period or at high doses face a greater risk of bone fracture, especially in the spine, hip or the wrist.
- People who have heartburn problems should refrain from consuming this pill for in case of instant pain relief
Adverse Effects of Nexium medication
Nexium is often administered in intensive care patients to prevent the development of ulcers, but there is an increased risk of catching pneumonia if this method is used.
- The risk of bone fractures increase when the elderly consume the medicine for a longer duration or in higher doses.
- Some commonly reported side effects are nausea, flatulence, diarrhea, head-ache and stomach pain. Allergic reactions are also possible in a few.
- Chest pain, increased heart rate, unusual bleeding and exhaustion are often reported as well. An emergency room visit is advised if the effects are severe.